Our science
Your skin has
a language.
Your skincare should speak it.
Your skin’s ability to renew depends on cells working together. Signals help coordinate that activity, while the moisture barrier helps preserve comfort at the surface. We look to these connected processes when selecting biomimetic peptides and complementary actives, considering each ingredient’s evidence, delivery, and role within the complete formula. Advanced science, translated into purposeful daily care.
Skin cell
A living part of your skin, receiving and responding to information around it.
Cell membrane
The boundary of the cell, where many signals are received.
Nucleus
Holds the cell’s DNA—the instructions used in its activity.
Peptide signal
A short chain of amino acids. Some peptide signals influence fibroblasts—the cells that make and maintain collagen—connecting cell communication with the remodeling of your skin’s supporting matrix.
Receptor
A protein that recognizes a particular signal and helps the cell respond.
Exosome messenger
A tiny membrane-bound vesicle carrying biological cargo. In laboratory models, certain exosomes influence fibroblast pathways involved in collagen production and matrix breakdown. Their source and cargo shape the response.
Cargo
The biological material carried within the vesicle.
- A peptide signal approaches a receptor.
- The receptor recognizes the signal.
- A response begins within the receiving cell.
- A vesicle is released from a compartment inside a cell.
- It travels through the space between cells.
- It meets another cell. Binding, uptake and delivery are distinct processes.
Within your skin / Matrix remodeling
A signal to the skin’s supporting cells.
In the dermis, fibroblasts make and maintain the matrix that supports your skin. Certain peptide signals can influence their activity—including collagen production. Remodeling is the ongoing balance of making, organizing and breaking down that matrix.
What the research shows
In cultured human fibroblasts, the peptide C16-KTTKS increased collagen production at particular concentrations. This is one example of a peptide influencing matrix-related activity; it does not establish that every peptide acts in the same way.
The animation illustrates a general principle: a signal is received and a response follows inside the cell. The receptor and downstream pathway depend on the particular signal. This view does not show a cosmetic ingredient reaching the dermis or demonstrate the results of a finished formula.
Within your skin / Matrix remodeling
Messages that can shape a cellular response.
Exosomes carry biological cargo between cells. In laboratory models, certain exosomes influence fibroblast pathways involved in collagen production and matrix breakdown. The response depends on their source, their cargo and the receiving cell.
Explore the remodeling pathways
TGF-β / SMAD is one signaling pathway involved in collagen production. In a study of UVB-exposed fibroblasts and mice, fibroblast-derived exosomes affected this pathway and reduced MMP-1, an enzyme involved in collagen breakdown.
MMPs help break down matrix proteins; TIMPs help regulate their activity. Research in three-dimensional human fibroblast cultures also found matrix-associated proteins within exosomes. Remodeling depends on the balance of these processes—not simply increasing collagen.
These studies help explain cell communication. They are not clinical evidence for RECOVER 04 or proof that topically applied vesicles reach the dermis. Binding to a cell, entering it and delivering cargo are separate events.
The language of your skin
01 / The signals you notice
What you notice
matters.
The way your skin looks and feels is where understanding begins. Dryness. Tightness. Uneven texture. Explore what you notice, what may be behind it, and where to focus your daily care.

Moisture + replenishment
Bring comfort back to your skin.
What you notice
When skin feels rough, looks flaky, or loses its softness through the day, moisture deserves your attention. Understanding what helps your skin hold onto hydration is the first step toward care that feels more comfortable.
What may be behind it
Your skin may be losing moisture faster than it can hold onto it. Weather, cleansing and the condition of your moisture barrier can all play a part.
Where to focus your care
Begin with gentle cleansing and a moisturizer that brings water and replenishing lipids together. Apply it while skin is still slightly damp.
Gentle cleansing + comfort
Skin that feels at ease.
What you notice
That drawn, uncomfortable feeling, especially after washing your face.
What may be behind it
A tight after-feel can be a clue that your cleansing routine is removing too much of your skin’s natural moisture. Hot water and frequent washing can contribute.
Where to focus your care
Use lukewarm water, choose a gentle cleanser and follow with moisturizer. A comfortable finish is a better goal than a squeaky-clean feeling.
Consistency + considered renewal
A smoother-looking surface.
What you notice
Rough patches, small bumps or a surface that no longer feels even.
What may be behind it
Texture has more than one explanation. Dryness, congestion and accumulated sun exposure can each change the way skin looks and feels.
Where to focus your care
Keep hydration and daily sun protection consistent. If you exfoliate, choose a method your skin tolerates and give it time between applications.
Gentleness + consistency
A calmer approach to clarity.
What you notice
Clogged pores or recurring breakouts, even when other areas feel dry.
What may be behind it
Oil and dead skin cells can collect in pores. Hormones, products and irritation can also influence breakouts; more aggressive cleansing is rarely the answer. The gut–skin axis deserves attention, too. Acne can be influenced by the gut microbiome and immune signaling.
Where to focus your care
Choose gentle, non-comedogenic care, avoid picking and let a consistent routine work. Look beyond the surface, too: notice whether breakouts follow your cycle, and discuss hormonal patterns or ongoing digestive concerns with a qualified clinician. Understanding the wider picture can help make your care more personal. Persistent or painful breakouts are a reason to seek a dermatologist’s guidance.
Simplicity + reassurance
Room for skin to settle.
What you notice
Stinging, discomfort or visible redness after a product, a change in weather or a busy routine.
What may be behind it
Skin can react to an ingredient or to doing too much at once. A visible reaction alone cannot tell you its cause.
Where to focus your care
Pause products that sting, simplify your routine and introduce new care gradually. Persistent redness or discomfort deserves individual advice.
Protection + visible renewal
A softer look. A considered ritual.
What you notice
Lines that linger, or feel more noticeable when your skin is dry.
What may be behind it
Moisture levels, repeated facial movement, time and sun exposure all influence the appearance of lines. These changes do not have a single cause.
Where to focus your care
Start with daily broad-spectrum SPF 30 or higher and consistent moisturization. Explore targeted ingredients with evidence for the appearance of fine lines.
Your skin is more than one signal.
Bring the details together in your personal Skin Signal profile.
02 / The language within
Our Biomems.
Inspired by your biology.
Chosen for your care.
Biomems is our name for biomimetic peptides—short chains of amino acids inspired by the body’s own structures and signals. Explore their individual roles in skincare, from the appearance of fine lines to smoother-looking texture and a more supple-looking complexion.
Some, like GHK, are naturally present in the body. Others are designed to echo aspects of its biology. Each has its own story—and a considered purpose in skincare.
Our Biomems / 01
Copper Tripeptide-1
A smoother, more supple-looking complexion.
Why it matters for your skin
A considered approach to visible renewal, with daily skin comfort and the experience of the complete formula in view.
Its connection to your body
Naturally present. Thoughtfully formulated.
GHK is a three-amino-acid peptide naturally found in the human body. It can bind copper to form GHK-Cu. Research explores its role in the signals involved in maintaining and renewing the skin’s supporting structure.
Its role in a formula
In topical skincare, GHK-Cu is studied for the appearance of lines, skin texture and hydration. It is the peptide at the heart of SIGNAL 01.
The research behind it
GHK-Cu has laboratory and topical research behind it. Results depend on the complete formula; ingredient research is not a finished-product result for AMINATIDE.
Research on GHK and copper (opens in a new tab)SIGNAL 01
Meet SIGNAL 01Our Biomems / 02
Palmitoyl Pentapeptide-4
Fine lines, visibly softened.
Why it matters for your skin
A peptide with human research behind its place in visible line care. The way it is delivered in a complete formula matters, too.
Its connection to your body
Inspired by a fragment of your own collagen.
Its five-amino-acid sequence comes from a fragment of type I procollagen, a precursor to collagen. The cosmetic peptide pairs that sequence with a fatty-acid component. It is inspired by the body’s own structures, rather than being identical to the unmodified fragment.
Its role in a formula
A controlled, 12-week study found that a moisturizer containing this peptide improved the appearance of fine lines and wrinkles compared with the same moisturizer without it.
The research behind it
The study involved 93 women and tested a specific moisturizer. It does not establish the performance of an AMINATIDE product or an eye-lifting effect.
Read the controlled human study (opens in a new tab)SIGNAL 01 / Visible line care
Meet SIGNAL 01Our Biomems / 03
Palmitoyl Tripeptide-5
Care for a firmer-looking complexion.
Why it matters for your skin
A different way to approach visible firmness: drawing on the signals that influence the skin’s supporting structure.
Its connection to your body
Designed to echo a natural signaling process.
Your body uses signals to help regulate collagen, a protein that gives skin its supporting structure. This laboratory-designed peptide is intended to echo part of that communication. It takes inspiration from the body’s biology; it does not occur naturally in this exact cosmetic form.
Its role in a formula
Its manufacturer has studied it for collagen-related activity and the appearance of wrinkles. We choose it as a complement to the copper peptide at the heart of SIGNAL 01.
The research behind it
The supporting evidence is primarily manufacturer research. Ingredient findings do not establish the performance of a finished AMINATIDE formula.
Explore the manufacturer’s research (opens in a new tab)SIGNAL 01
Meet SIGNAL 01Our Biomems / 04
Palmitoyl Tripeptide-1
Support for smoother-looking skin.
Why it matters for your skin
A complementary approach to the appearance of skin’s surface: smoother, more supple-looking skin.
Its connection to your body
A familiar sequence, adapted for skincare.
This peptide uses the GHK amino-acid sequence with an attached fatty-acid component. It draws on the idea that small protein fragments can act as messages within the skin. Unlike GHK-Cu, this ingredient is not the copper-bound complex.
Its role in a formula
It is paired with Palmitoyl Tetrapeptide-7 in the Matrixyl 3000 peptide system, which the manufacturer studies for visible wrinkle care.
The research behind it
The cited performance research concerns the paired ingredient system. It should not be read as proof of this peptide alone or of an AMINATIDE formula.
Explore the paired peptide system (opens in a new tab)The peptide library / Visible smoothing
Our formulation philosophyOur Biomems / 05
Palmitoyl Tetrapeptide-7
A partner in visible smoothing.
Why it matters for your skin
An example of why we consider ingredients together: the relationship between complementary actives is part of the formulation story.
Its connection to your body
Inspired by the body’s peptide communication.
This four-amino-acid cosmetic peptide has an attached fatty-acid component. It takes inspiration from peptide communication and is studied with Palmitoyl Tripeptide-1.
Its role in a formula
Together with Palmitoyl Tripeptide-1, it forms the Matrixyl 3000 system. Manufacturer research focuses on the appearance of wrinkles and the skin’s supporting matrix.
The research behind it
The available manufacturer research evaluates the combination. A result for the blend is not a result for this peptide in isolation.
Explore the paired peptide system (opens in a new tab)The peptide library / Visible smoothing
Our formulation philosophyOur Biomems / 06
Acetyl Tetrapeptide-5
A fresher, less puffy-looking eye area.
Why it matters for your skin
Targeted care for an area where a rested appearance can make a visible difference.
Its connection to your body
Designed around the needs of delicate skin.
The way fluid moves and proteins behave can influence the appearance of the eye area. This laboratory-designed peptide has been studied by its manufacturer for processes related to fluid accumulation and protein glycation. It is not a peptide known to occur in this exact form naturally in the body.
Its role in a formula
Known as the peptide in Eyeseryl, it has manufacturer research focused on the appearance of under-eye bags and puffiness. Its focus is the delicate eye contour.
The research behind it
The evidence is manufacturer-led and specific to the tested ingredient preparations. It does not establish the performance of a finished AMINATIDE formula.
Read the original manufacturer’s research (opens in a new tab)The peptide library / Eye contour care
Our formulation philosophyTurn to discover 01 / 06
Hover to discover. Tap to discover. Drag to turn.
Every peptide has a purpose.
The complete formula brings it to life.
The AMINA Complex™
Intelligent signals.
Visible renewal.
Your skin sets the purpose. The formula follows.
01 / Visible renewal
A smoother, firmer-looking complexion.
Peptides are at the heart of AMINATIDE, beginning with the GHK-Cu–anchored SIGNAL 01. Complementary actives and layered hydration are considered together in a silky formula made for daily care.
SIGNAL 0102 / Supple hydration
Hydration you can feel.
Hydrating and skin-conditioning ingredients are considered throughout the leave-on formulas, with attention to how skin feels after application and how each layer fits into your routine.
Discover the Renewal Duo03 / Barrier comfort
The comfort that stays with you.
Smoother-looking skin. Lasting hydration. Greater comfort. We select actives for the part they can play in a clear skin objective, with research informing each choice.
Our house standard04 / Daily pleasure
Pleasure in every ritual.
The slip of a serum. The cushion of a cream. The finish that feels right on your skin. Sensorial quality is part of our development standard, creating a ritual you can look forward to.
Find your ritualTHE AMINA COMPLEX™ connects every ingredient, every texture and every quality decision to a clear purpose for your skin. Each product has its own composition, shaped by the care it is intended to provide.
Purpose in every formula.
Pleasure in every ritual.
The research behind the ritual
Understand the science
behind your care.
You deserve to understand why an ingredient earns its place. Explore the research that informs our choices, what the studies found, and what those findings mean.
The findings below come from research on specific ingredients and formulations. AMINATIDE’s own finished-product results will be shared after testing.
01 / Copper tripeptide-1Softer-looking lines.
Better-hydrated skin.
An eight-week study of a serum combining GHK-Cu with a ferment extract reported improved wrinkle measurements and skin barrier measures. Thirty of 32 women completed the study. It had no control group; the findings apply to the combined formula, not GHK-Cu alone.
Wang et al. · Skin Research and Technology · 2026
Read the study ↗ (opens in a new tab)02 / Palmitoyl pentapeptide-4Fine lines,
visibly softened.
A 12-week, double-blind, split-face study in 93 women compared a moisturizer containing 3 ppm pal-KTTKS with the same moisturizer without the peptide. The peptide formula improved the appearance of fine lines and wrinkles versus the control. This industry-authored research studied its own formula, not an AMINATIDE product.
Robinson et al. · International Journal of Cosmetic Science · 2005
Read the study ↗ (opens in a new tab)Quality by design
Before it
reaches your skin.
Your confidence begins with the care behind the formula. From ingredient selection and texture to safety, stability, and compatibility testing, every formula must meet our standards before it becomes part of your ritual.
Meet the HouseBegin with purpose.
Define the care the formula should provide: its skin objective, intended benefits, texture and place in your daily ritual.
Consider every detail.
Select ingredients for their quality and role. Refine their concentrations, compatibility and texture.
Put the formula to the test.
Evaluate safety, stability, preservation and packaging compatibility, with testing to substantiate the benefits we communicate.
Release with care.
Review each finished batch against its specifications, with traceability and documented quality approval before release.
The Signal
You’re invited.
Be here before the first reveal.
Join THE SIGNAL for first looks and private pre-sale invitations.
Our first chapter. Arriving 2027.





